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Dorsalgia

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_DORSALGIA

causalgia: Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia , not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

68572

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Remove individuals based on genotype QC

66041

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M13_DORSALGIA

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 66041 40601 25440
Unadjusted prevalence (%) 16.03 17.63 14.00
Mean age at first event (years) 50.62 49.30 52.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.86 [1.65, 2.10] 1.0e-23 6422
15 years 0.01 1.18 [1.07, 1.32] 1.7e-3 2400
5 years 0.00 2.64 [2.41, 2.89] 1.9e-96 1707
1 year 0.00 7.02 [6.27, 7.86] <1e-100 919

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_DORSALGIA – Dorsalgia
GWS hits: 14

Survival analyses between endpoints

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Plot

before Dorsalgia
after Dorsalgia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Dorsalgia

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Endpoint not on priority list, no data to show.