≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Polyarteritis with lung involvement [Churg-Strauss]/EGPA

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_CHURGSTRAUSS

Churg-Strauss syndrome: Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, is a systemic vasculitis of small-to medium vessels, characterized by asthma, transient pulmonary infiltrates, and hypereosinophilia.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M30.1
Hospital discharge: ICD-9 4460B
Cause of death: ICD-10 M30.1
Cause of death: ICD-9 4460B

2 out of 7 registries used, show all original rules.

111

diagram downward connector

Check minimum number of events None

111

diagram downward connector

Include endpoints None

111

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

107

diagram downward connector
M13_CHURGSTRAUSS

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30
Name in latin Polyarteritis nodosa cum manifestationibus pulmonalibus

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 107 69 38
Unadjusted prevalence (%) 0.03 0.03 0.02
Mean age at first event (years) 51.93 51.20 53.25

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_CHURGSTRAUSS – Polyarteritis with lung involvement [Churg-Strauss]/EGPA
GWS hits:

Survival analyses between endpoints

↥

Plot

before Polyarteritis with lung involvement [Churg-Strauss]/EGPA
after Polyarteritis with lung involvement [Churg-Strauss]/EGPA

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Polyarteritis with lung involvement [Churg-Strauss]/EGPA

↥

Endpoint not on priority list, no data to show.