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Urticaria

DOID EFO MESH SNOMED Endpoint Browser PheWeb

L12_URTICARIA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

11663

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Remove individuals based on genotype QC

11186

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L12_URTICARIA

Control definitions

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 11186 8025 3161
Unadjusted prevalence (%) 2.72 3.49 1.74
Mean age at first event (years) 41.14 40.68 42.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.13 [0.77, 1.65] 5.3e-1 602
15 years 0.01 0.89 [0.65, 1.20] 4.4e-1 244
5 years 0.00 1.93 [1.46, 2.54] 3.0e-6 140
1 year 0.00 4.26 [3.02, 5.99] 1.1e-16 55

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICARIA – Urticaria
GWS hits: 5

Survival analyses between endpoints

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Plot

before Urticaria
after Urticaria

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Urticaria

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Endpoint not on priority list, no data to show.