Urticaria

L12_URTICARIA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

11186

diagram downward connector
L12_URTICARIA

Control definitions

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 11186 8025 3161
Unadjusted prevalence (%) 2.72 3.49 1.74
Mean age at first event (years) 41.14 40.68 42.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.13 [0.77, 1.65] 5.3e-1 602
15 years 0.01 0.89 [0.65, 1.20] 4.4e-1 244
5 years 0.00 1.93 [1.46, 2.54] 3.0e-6 140
1 year 0.00 4.26 [3.02, 5.99] 1.1e-16 55

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_URTICARIA – Urticaria
GWS hits: 5

Survival analyses between endpoints

Plot

before Urticaria
after Urticaria

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Urticaria

Endpoint not on priority list, no data to show.