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Disorders of skin appendages

DOID MESH Endpoint Browser PheWeb

L12_DISORDSKINAPPENDIX

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L60-L75
Cause of death: ICD-10 L60-L75

2 out of 7 registries used, show all original rules.

17494

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Check minimum number of events None

17494

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Include endpoints

18795

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Remove individuals based on genotype QC

18076

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L12_DISORDSKINAPPENDIX

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 18076 11061 7015
Unadjusted prevalence (%) 4.39 4.80 3.86
Mean age at first event (years) 45.38 44.39 46.94

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.94 [1.41, 2.68] 5.6e-5 1191
15 years 0.01 1.46 [1.13, 1.88] 4.1e-3 558
5 years 0.00 2.42 [1.96, 3.00] 4.7e-16 302
1 year 0.00 3.21 [2.41, 4.26] 1.2e-15 76

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_DISORDSKINAPPENDIX – Disorders of skin appendages
GWS hits: 6

Survival analyses between endpoints

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Plot

before Disorders of skin appendages
after Disorders of skin appendages

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Drugs most likely to be purchased after Disorders of skin appendages

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Endpoint not on priority list, no data to show.