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Acne

DOID EFO MESH Endpoint Browser PheWeb

L12_ACNE

acne: An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L70
Cause of death: ICD-10 L70

2 out of 7 registries used, show all original rules.

3153

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Check minimum number of events None

3153

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Include endpoints

3402

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Remove individuals based on genotype QC

3245

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L12_ACNE

Control definitions

Control exclude L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L60-L75
Name in latin Acne

Summary Statistics

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Key figures

All Female Male
Number of individuals 3245 2068 1177
Unadjusted prevalence (%) 0.79 0.90 0.65
Mean age at first event (years) 28.01 28.43 27.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.12 [2.01, 8.45] 1.1e-4 73
15 years 0.03 3.38 [1.82, 6.27] 1.2e-4 32
5 years 0.01 6.24 [3.34, 11.68] 9.9e-9 16
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ACNE – Acne
GWS hits: 5

Survival analyses between endpoints

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Plot

before Acne
after Acne

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acne

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Endpoint not on priority list, no data to show.