Other and unspecified atrophic disorders of skin

L12_ATROPHICSKINNAS

skin atrophy: The structural changes and the signs and symptoms of chronologically aged skinand those of corticosteroid induced chronicatrophyof theskinare partially very similar.Thinningof epidermis and laxity as well as dryness, purpura and echymoses occur in both conditions.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L90.8, L90.9
Hospital discharge: ICD-9 7018X
Cause of death: ICD-10 L90.8, L90.9
Cause of death: ICD-9 7018X

2 out of 7 registries used, show all original rules.

125

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Check minimum number of events None

125

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Include endpoints None

125

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Remove individuals based on genotype QC

124

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L12_ATROPHICSKINNAS

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 124 109 15
Unadjusted prevalence (%) 0.03 0.05 0.01
Mean age at first event (years) 55.56 55.72 54.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_ATROPHICSKINNAS – Other and unspecified atrophic disorders of skin
GWS hits:

Survival analyses between endpoints

Plot

before Other and unspecified atrophic disorders of skin
after Other and unspecified atrophic disorders of skin

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Drugs most likely to be purchased after Other and unspecified atrophic disorders of skin

Endpoint not on priority list, no data to show.