Atrophic disorders of skin


skin atrophy: The structural changes and the signs and symptoms of chronologically aged skinand those of corticosteroid induced chronicatrophyof theskinare partially very similar.Thinningof epidermis and laxity as well as dryness, purpura and echymoses occur in both conditions.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L90
Cause of death: ICD-10 L90

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions


Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Morbositates atrophicae cutis

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 4293 3569 724
Unadjusted prevalence (%) 1.04 1.55 0.40
Mean age at first event (years) 54.84 56.07 48.75


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.49 [0.78, 2.81] 2.2e-1 195
15 years 0.01 1.11 [0.68, 1.83] 6.8e-1 94
5 years 0.00 1.63 [1.05, 2.54] 3.0e-2 45
1 year 0.00 1.97 [0.98, 3.95] 5.7e-2 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: L12_ATROPHICSKIN – Atrophic disorders of skin
GWS hits: 2

Survival analyses between endpoints


before Atrophic disorders of skin
after Atrophic disorders of skin

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Drugs most likely to be purchased after Atrophic disorders of skin

Endpoint not on priority list, no data to show.