Idiopathic pulmonary fibrosis

IPF

idiopathic pulmonary fibrosis: Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J84.1
Cause of death: ICD-10 J84.1

2 out of 7 registries used, show all original rules.

2264

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Check minimum number of events None

2264

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Include endpoints None

2264

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Remove individuals based on genotype QC

2189

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IPF

Control definitions

Control exclude ILD_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF5
Parent code in ICD-10 J84
Name in latin Morbus pulmonum interstitialis cum fibrosi

Summary Statistics

Key figures

All Female Male
Number of individuals 2189 732 1457
Unadjusted prevalence (%) 0.53 0.32 0.80
Mean age at first event (years) 69.80 66.86 71.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: IPF – Idiopathic pulmonary fibrosis
GWS hits: 10

Survival analyses between endpoints

Plot

before Idiopathic pulmonary fibrosis
after Idiopathic pulmonary fibrosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Idiopathic pulmonary fibrosis