≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Valvular heart disease excluding rheumatic fever

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_VHD

heart valve disease: A disease involving the cardial valve.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

23606

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

22817

diagram downward connector
I9_VHD

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Similar endpoints

↥

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 22817 9606 13211
Unadjusted prevalence (%) 5.54 4.17 7.27
Mean age at first event (years) 65.91 65.40 66.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.56 [3.06, 4.14] 8.7e-62 5021
15 years 0.01 1.85 [1.63, 2.10] 3.6e-21 1946
5 years 0.01 3.65 [3.29, 4.04] <1e-100 1622
1 year 0.00 10.67 [9.51, 11.97] <1e-100 1029

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: I9_VHD – Valvular heart disease excluding rheumatic fever
GWS hits: 12

Survival analyses between endpoints

↥

Plot

before Valvular heart disease excluding rheumatic fever
after Valvular heart disease excluding rheumatic fever

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Valvular heart disease excluding rheumatic fever

↥

Endpoint not on priority list, no data to show.