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Varicose veins

DOID MESH Endpoint Browser PheWeb

I9_VARICVE

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I83
Hospital discharge: ICD-9 454
Hospital discharge: ICD-8 454
Cause of death: ICD-10 I83
Cause of death: ICD-9 454
Cause of death: ICD-8 454

2 out of 7 registries used, show all original rules.

32596

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Check minimum number of events None

32596

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Include endpoints None

32596

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Remove individuals based on genotype QC

31719

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I9_VARICVE

Control definitions

Control exclude I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I80-I89
Name in latin Varices membrorum inferiorum

Summary Statistics

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Key figures

All Female Male
Number of individuals 31719 23389 8330
Unadjusted prevalence (%) 7.70 10.16 4.58
Mean age at first event (years) 45.80 43.78 51.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.02 [0.90, 1.14] 8.1e-1 4632
15 years 0.01 0.78 [0.70, 0.86] 6.9e-7 1748
5 years 0.00 1.07 [0.96, 1.20] 2.2e-1 618
1 year 0.00 2.07 [1.76, 2.45] 5.1e-18 212

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_VARICVE – Varicose veins
GWS hits: 159

Survival analyses between endpoints

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Plot

before Varicose veins
after Varicose veins

loading spinner Loading survival analyses plot