Hypotension

I9_HYPOTE

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I95
Hospital discharge: ICD-9 458
Hospital discharge: ICD-8 4580
Cause of death: ICD-10 I95
Cause of death: ICD-9 458
Cause of death: ICD-8 4580

2 out of 7 registries used, show all original rules.

5092

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Check minimum number of events None

5092

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Include endpoints None

5092

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Remove individuals based on genotype QC

4924

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I9_HYPOTE

Control definitions

Control exclude I9_OTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I95-I99
Name in latin Hypotensio (arterialis)

Summary Statistics

Key figures

All Female Male
Number of individuals 4924 2047 2877
Unadjusted prevalence (%) 1.20 0.89 1.58
Mean age at first event (years) 70.28 67.65 72.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 7.67 [6.49, 9.05] <1e-100 1559
15 years 0.02 2.20 [1.87, 2.60] 1.3e-20 402
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HYPOTE – Hypotension
GWS hits:

Survival analyses between endpoints

Plot

before Hypotension
after Hypotension

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Drugs most likely to be purchased after Hypotension

Endpoint not on priority list, no data to show.