Endocarditis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_ENDOCARD

endocarditis: Inflammation of the endocardium.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I33, I38, I39*

Hospital discharge: ICD-9 421|4249|0932A

Hospital discharge: ICD-8 421

Cause of death: ICD-10 I33, I38, I39*

Cause of death: ICD-9 421|4249|0932A

Cause of death: ICD-8 421

2 out of 7 registries used, show all original rules.

1072

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Check minimum number of events None

1072

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Include endpoints None

1072

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Remove individuals based on genotype QC

1027

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I9_ENDOCARD

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF6

NAME	I9_ENDOCARD
CONTROL_EXCLUDE	I9_OTHHEART
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I33\|I38\|I39
HD_ICD_9	421\|4249\|0932A
HD_ICD_8	421
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I33\|I38\|I39
COD_ICD_9	421\|4249\|0932A
COD_ICD_8	421
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Endocarditis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1027	293	734
Unadjusted prevalence (%)	0.25	0.13	0.40
Mean age at first event (years)	59.35	55.75	60.78

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.19	10.08 [6.92, 14.68]	2.5e-33	297
15 years	0.02	3.49 [2.53, 4.82]	2.9e-14	85
5 years	0.01	7.20 [5.24, 9.89]	4.3e-34	86
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_ENDOCARD – Endocarditis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Endocarditis
after Endocarditis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Endocarditis

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Endpoint not on priority list, no data to show.