Endocarditis

I9_ENDOCARD

endocarditis: Inflammation of the endocardium.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I33, I38, I39*
Hospital discharge: ICD-9 421|4249|0932A
Hospital discharge: ICD-8 421
Cause of death: ICD-10 I33, I38, I39*
Cause of death: ICD-9 421|4249|0932A
Cause of death: ICD-8 421

2 out of 7 registries used, show all original rules.

1072

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Check minimum number of events None

1072

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Include endpoints None

1072

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Remove individuals based on genotype QC

1027

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I9_ENDOCARD

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 1027 293 734
Unadjusted prevalence (%) 0.25 0.13 0.40
Mean age at first event (years) 59.35 55.75 60.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 10.08 [6.92, 14.68] 2.5e-33 297
15 years 0.02 3.49 [2.53, 4.82] 2.9e-14 85
5 years 0.01 7.20 [5.24, 9.89] 4.3e-34 86
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_ENDOCARD – Endocarditis
GWS hits: 1

Survival analyses between endpoints

Plot

before Endocarditis
after Endocarditis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Endocarditis

Endpoint not on priority list, no data to show.