≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Cerebral atherosclerosis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_CEREBATHER

cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I67.2
Hospital discharge: ICD-9 4370
Hospital discharge: ICD-8 437
Cause of death: ICD-10 I67.2
Cause of death: ICD-9 4370
Cause of death: ICD-8 437

2 out of 7 registries used, show all original rules.

354

diagram downward connector

Check minimum number of events None

354

diagram downward connector

Include endpoints None

354

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

342

diagram downward connector
I9_CEREBATHER

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Atherosclerosis cerebralis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 342 117 225
Unadjusted prevalence (%) 0.08 0.05 0.12
Mean age at first event (years) 70.72 70.35 70.91

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: I9_CEREBATHER – Cerebral atherosclerosis
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Cerebral atherosclerosis
after Cerebral atherosclerosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cerebral atherosclerosis

↥

Endpoint not on priority list, no data to show.