Cerebral atherosclerosis


cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I67.2
Hospital discharge: ICD-9 4370
Hospital discharge: ICD-8 437
Cause of death: ICD-10 I67.2
Cause of death: ICD-9 4370
Cause of death: ICD-8 437

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Atherosclerosis cerebralis

Summary Statistics

Key figures

All Female Male
Number of individuals 342 117 225
Unadjusted prevalence (%) 0.08 0.05 0.12
Mean age at first event (years) 70.72 70.35 70.91


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_CEREBATHER – Cerebral atherosclerosis
GWS hits: 1

Survival analyses between endpoints


before Cerebral atherosclerosis
after Cerebral atherosclerosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cerebral atherosclerosis

Endpoint not on priority list, no data to show.