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AV-block

DOID MESH Endpoint Browser PheWeb

I9_AVBLOCK

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I44.0, I44.1, I44.2, I44.3
Hospital discharge: ICD-9 426[0-1]
Cause of death: ICD-10 I44.0, I44.1, I44.2, I44.3
Cause of death: ICD-9 426[0-1]

2 out of 7 registries used, show all original rules.

6306

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Check minimum number of events None

6306

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Include endpoints None

6306

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Remove individuals based on genotype QC

6097

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I9_AVBLOCK

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 6097 1934 4163
Unadjusted prevalence (%) 1.48 0.84 2.29
Mean age at first event (years) 69.96 67.05 71.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.19 [2.42, 4.22] 2.4e-16 1622
15 years 0.01 1.45 [1.16, 1.81] 9.9e-4 564
5 years 0.00 3.33 [2.83, 3.93] 1.0e-46 615
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_AVBLOCK – AV-block
GWS hits: 5

Survival analyses between endpoints

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Plot

before AV-block
after AV-block

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after AV-block

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Endpoint not on priority list, no data to show.