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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Aortic valve malfunction, age under 60 years

I9_AORTVALV_EARLY

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Pre-conditions EVENT_AGE < 60
Hospital Discharge: ICD-10 I35.0, I35.1, I35.2, I35.8
Hospital discharge: ICD-9 4242[A-C]
Cause of death: ICD-10 I35.0, I35.1, I35.2, I35.8
Cause of death: ICD-9 4242[A-C]

2 out of 7 registries used, show all original rules.

3003

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Check minimum number of events None

3003

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Include endpoints None

3003

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Remove individuals based on genotype QC

2900

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I9_AORTVALV_EARLY

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Summary Statistics

Key figures

All Female Male
Number of individuals 2900 1025 1875
Unadjusted prevalence (%) 0.70 0.45 1.03
Mean age at first event (years) 48.54 47.73 48.99

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: I9_AORTVALV_EARLY – Aortic valve malfunction, age under 60 years
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Aortic valve malfunction, age under 60 years

Endpoint not on priority list, no data to show.