Cerebral aneurysm, nonruptured

I9_ANEURYSM

brain aneurysm: A congenital or acquired aneurysm within the cranium.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I67.1
Hospital discharge: ICD-9 4373
Cause of death: ICD-10 I67.1
Cause of death: ICD-9 4373

2 out of 7 registries used, show all original rules.

2846

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Check minimum number of events None

2846

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Include endpoints None

2846

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Remove individuals based on genotype QC

2783

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I9_ANEURYSM

Control definitions

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Aneurysma encephali non ruptum

Summary Statistics

Key figures

All Female Male
Number of individuals 2783 1781 1002
Unadjusted prevalence (%) 0.68 0.77 0.55
Mean age at first event (years) 56.87 56.25 57.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.23 [1.15, 4.35] 1.8e-2 365
15 years 0.01 1.76 [1.08, 2.88] 2.3e-2 162
5 years 0.01 4.02 [2.71, 5.97] 5.6e-12 99
1 year 0.00 9.17 [5.87, 14.32] 1.8e-22 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_ANEURYSM – Cerebral aneurysm, nonruptured
GWS hits: 4

Survival analyses between endpoints

Plot

before Cerebral aneurysm, nonruptured
after Cerebral aneurysm, nonruptured

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Drugs most likely to be purchased after Cerebral aneurysm, nonruptured

Endpoint not on priority list, no data to show.