This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Hypothyroidism and >3 levothyroxin purchases
DOID EFO MESH SNOMED Endpoint Browser
HYPOTHY_PURCHASE
hypothyroidism: Abnormally low levels of thyroid hormone.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions
HYPOTHYROIDISM
54806
Check pre-conditions, main-only, mode, registry filters None
0 out of 7 registries used, show all original rules.
0
Check minimum number of events None
0
Remove individuals based on genotype QC
52222
HYPOTHY_PURCHASE
Control definitions
Control exclude
E4_MALNUTRITION, E4_DIABETES, I9_CVD, C3_CANCER, MENINGITIS, ENCEPHALITIS, HYPOTHYROIDISM, D3_ANAEMIA, F5_ALLANXIOUS, F5_MOOD, F5_SCHIZO, F5_BEHEMOCHILD, F5_UNSMENDIS, ANOSMIA, ANTIDEPRESSANTS
Control conditions
not HYPOTHYROIDISM
Extra metadata
First used in FinnGen datafreeze
DF3
No data for upset plot.
No data for upset table.
Similar endpoints
↥List of similar endpoints to
Hypothyroidism and >3 levothyroxin purchases
based on the number of shared cases.
Broader endpoints:
- Hypothyroidism, levothyroxine purchases
- Hypothyroidism, other/unspecified
- Hypothyroidism (congenital or acquired)
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 52222 | 41726 | 10496 |
| Unadjusted prevalence (%) | 12.68 | 18.12 | 5.78 |
| Mean age at first event (years) | 51.58 | 49.87 | 58.38 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: HYPOTHY_PURCHASE – Hypothyroidism and >3 levothyroxin purchases
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Hypothyroidism and >3 levothyroxin purchases
↥Endpoint not on priority list, no data to show.