Hypothyroidism, strict autoimmune

E4_HYTHY_AI_STRICT

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not E4_HYTHY_AI_EXCL

416786

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

46925

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Remove individuals based on genotype QC

45320

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E4_HYTHY_AI_STRICT

Control definitions

Control exclude AUTOIMMUNE
Control conditions not E4_HYTHY_AI_EXCL

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

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Key figures

All Female Male
Number of individuals 45320 36229 9091
Unadjusted prevalence (%) 11.00 15.74 5.00
Mean age at first event (years) 51.54 49.68 58.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.83 [1.59, 2.11] 1.9e-16 4021
15 years 0.01 1.31 [1.16, 1.48] 9.7e-6 1966
5 years 0.00 2.04 [1.83, 2.27] 8.3e-38 938
1 year 0.00 1.96 [1.63, 2.35] 8.1e-13 162

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 199

Survival analyses between endpoints

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Plot

before Hypothyroidism, strict autoimmune
after Hypothyroidism, strict autoimmune

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, strict autoimmune

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Endpoint not on priority list, no data to show.