Hypothyroidism, strict autoimmune

E4_HYTHY_AI_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not E4_HYTHY_AI_EXCL

416786

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

46925

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Remove individuals based on genotype QC

45320

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E4_HYTHY_AI_STRICT

Control definitions

Control exclude AUTOIMMUNE
Control conditions not E4_HYTHY_AI_EXCL

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 45320 36229 9091
Unadjusted prevalence (%) 11.00 15.74 5.00
Mean age at first event (years) 51.54 49.68 58.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.83 [1.59, 2.11] 1.9e-16 4021
15 years 0.01 1.31 [1.16, 1.48] 9.7e-6 1966
5 years 0.00 2.04 [1.83, 2.27] 8.3e-38 938
1 year 0.00 1.96 [1.63, 2.35] 8.1e-13 162

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 199

Survival analyses between endpoints

Plot

before Hypothyroidism, strict autoimmune
after Hypothyroidism, strict autoimmune

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, strict autoimmune

Endpoint not on priority list, no data to show.