Other/unspecified disorders of vestibular function

H8_VESTIFUNCNAS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H81.8, H81.9
Hospital discharge: ICD-9 386[8-9]
Cause of death: ICD-10 H81.8, H81.9
Cause of death: ICD-9 386[8-9]

2 out of 7 registries used, show all original rules.

1041

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Check minimum number of events None

1041

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Include endpoints None

1041

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Remove individuals based on genotype QC

986

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H8_VESTIFUNCNAS

Control definitions

Control exclude H8_INNER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 986 599 387
Unadjusted prevalence (%) 0.24 0.26 0.21
Mean age at first event (years) 59.13 58.39 60.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.79 [2.04, 3.81] 1.1e-10 135
15 years 0.01 1.43 [0.99, 2.08] 5.8e-2 59
5 years 0.00 2.35 [1.53, 3.62] 1.0e-4 33
1 year 0.00 3.74 [1.91, 7.33] 1.2e-4 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_VESTIFUNCNAS – Other/unspecified disorders of vestibular function
GWS hits:

Survival analyses between endpoints

Plot

before Other/unspecified disorders of vestibular function
after Other/unspecified disorders of vestibular function

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Drugs most likely to be purchased after Other/unspecified disorders of vestibular function

Endpoint not on priority list, no data to show.