Disorders of vestibular function (Vertigo)

H8_VERTIGO

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

16443

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H8_VERTIGO

Control definitions

Control exclude H8_INNER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 16443 10642 5801
Unadjusted prevalence (%) 3.99 4.62 3.19
Mean age at first event (years) 58.12 56.92 60.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.47 [1.14, 1.89] 3.0e-3 1434
15 years 0.01 1.03 [0.85, 1.24] 8.0e-1 659
5 years 0.00 1.80 [1.50, 2.17] 4.1e-10 382
1 year 0.00 2.84 [2.23, 3.62] 4.3e-17 114

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_VERTIGO – Disorders of vestibular function (Vertigo)
GWS hits: 3

Survival analyses between endpoints

Plot

before Disorders of vestibular function (Vertigo)
after Disorders of vestibular function (Vertigo)

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Drugs most likely to be purchased after Disorders of vestibular function (Vertigo)

Endpoint not on priority list, no data to show.