Other and unspecified disorders of vitreous body

H7_VITROTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H43.8, H43.9
Hospital discharge: ICD-9 3792A
Hospital discharge: ICD-8 37840
Cause of death: ICD-10 H43.8, H43.9
Cause of death: ICD-9 3792A
Cause of death: ICD-8 37840

2 out of 7 registries used, show all original rules.

13553

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Check minimum number of events None

13553

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Include endpoints None

13553

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Remove individuals based on genotype QC

13168

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H7_VITROTH

Control definitions

Control exclude H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 13168 8832 4336
Unadjusted prevalence (%) 3.20 3.84 2.39
Mean age at first event (years) 63.15 62.15 65.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.48 [1.12, 1.96] 6.4e-3 731
15 years 0.01 1.01 [0.77, 1.31] 9.7e-1 385
5 years 0.00 1.63 [1.29, 2.07] 4.2e-5 207
1 year 0.00 2.28 [1.64, 3.16] 8.4e-7 53

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_VITROTH – Other and unspecified disorders of vitreous body
GWS hits:

Survival analyses between endpoints

Plot

before Other and unspecified disorders of vitreous body
after Other and unspecified disorders of vitreous body

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Drugs most likely to be purchased after Other and unspecified disorders of vitreous body

Endpoint not on priority list, no data to show.