Disorders of vitreous body

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H7_VITRBODYGLOBE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H43

Cause of death: ICD-10 H43

2 out of 7 registries used, show all original rules.

16983

Check minimum number of events None

16983

Include endpoints

H7_VITRPROLAPSE

H7_VITRHAEMORR

H7_VITRCRYSTAL

H7_VITROPACIT

H7_VITROTH

17099

Remove individuals based on genotype QC

16606

H7_VITRBODYGLOBE

Control definitions

Control exclude H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H43-H45

Name in latin Morbositates corporis vitrei

NAME	H7_VITRBODYGLOBE
CONTROL_EXCLUDE	H7_VITREOUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H7_VITRPROLAPSE\|H7_VITRHAEMORR\|H7_VITRCRYSTAL\|H7_VITROPACIT\|H7_VITROTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H43
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H43
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Disorders of vitreous body based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	16606	10500	6106
Unadjusted prevalence (%)	4.03	4.56	3.36
Mean age at first event (years)	62.06	61.20	63.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.08 [1.44, 3.01]	9.5e-5	1276
15 years	0.01	1.51 [1.20, 1.91]	5.2e-4	648
5 years	0.00	2.39 [1.96, 2.92]	1.2e-17	381
1 year	0.00	3.01 [2.31, 3.91]	2.0e-16	93

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_VITRBODYGLOBE – Disorders of vitreous body
GWS hits: 3

Survival analyses between endpoints

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Plot

before Disorders of vitreous body
after Disorders of vitreous body

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Table

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Drugs most likely to be purchased after Disorders of vitreous body

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Endpoint not on priority list, no data to show.

≡ Risteys

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