Other and unspecified glaucoma

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H7_GLAUCNAS

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.8, H40.9

Hospital discharge: ICD-9 3656X|3656C|365[8-9]

Hospital discharge: ICD-8 3752|3759

Hospital discharge: excluded ICD-8 37597

Cause of death: ICD-10 H40.8, H40.9

Cause of death: ICD-9 3656X|3656C|365[8-9]

Cause of death: ICD-8 3752|3759

Cause of death: excluded ICD-8 37597

2 out of 7 registries used, show all original rules.

1967

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Check minimum number of events None

1967

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Include endpoints None

1967

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Remove individuals based on genotype QC

1894

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H7_GLAUCNAS

Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	H7_GLAUCNAS
CONTROL_EXCLUDE	H7_GLAUCOMA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H40[8-9]
HD_ICD_9	3656X\|3656C\|365[8-9]
HD_ICD_8	3752\|3759
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL	37597
COD_MAINONLY
COD_ICD_10	H40[8-9]
COD_ICD_9	3656X\|3656C\|365[8-9]
COD_ICD_8	3752\|3759
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL	37597
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Other and unspecified glaucoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1894	1036	858
Unadjusted prevalence (%)	0.46	0.45	0.47
Mean age at first event (years)	66.10	66.51	65.61

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	3.24 [2.46, 4.27]	7.9e-17	440
15 years	0.01	1.39 [1.04, 1.84]	2.5e-2	160
5 years	0.00	3.29 [2.56, 4.22]	1.3e-20	159
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCNAS – Other and unspecified glaucoma
GWS hits: 4

Survival analyses between endpoints

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Plot

before Other and unspecified glaucoma
after Other and unspecified glaucoma

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Table

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Drugs most likely to be purchased after Other and unspecified glaucoma

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Endpoint not on priority list, no data to show.