Narcolepsy and cataplexy


narcolepsy with cataplexy: Narcolepsy with cataplexy is a sleep disorder characterized by excessive day-time sleepiness associated with uncontrollable sleep urges and cataplexy (loss of muscle tone often triggered by pleasant emotions).

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G47.4
Hospital discharge: ICD-9 347[0-1]
Hospital discharge: ICD-8 34700
Cause of death: ICD-10 G47.4
Cause of death: ICD-9 347[0-1]
Cause of death: ICD-8 34700
KELA reimbursements: KELA codes 214

3 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G47
Name in latin Narcolepsia

Summary Statistics

Key figures

All Female Male
Number of individuals 198 112 86
Unadjusted prevalence (%) 0.05 0.05 0.05
Mean age at first event (years) 39.77 36.57 43.93


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_NARCOCATA – Narcolepsy and cataplexy
GWS hits:

Survival analyses between endpoints


before Narcolepsy and cataplexy
after Narcolepsy and cataplexy

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Drugs most likely to be purchased after Narcolepsy and cataplexy

Endpoint not on priority list, no data to show.