Migraine with aura

G6_MIGRAINE_WITH_AURA

migraine with aura: A migraine disorder characterized by episodes that are preceded by focal neurological symptoms.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G43.1#
Hospital discharge: ICD-9 3460
Cause of death: ICD-10 G43.1#
Cause of death: ICD-9 3460

2 out of 7 registries used, show all original rules.

9272

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Check minimum number of events None

9272

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Include endpoints None

9272

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Remove individuals based on genotype QC

8970

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G6_MIGRAINE_WITH_AURA

Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 G43
Name in latin Hemicrania cum aura

Summary Statistics

Key figures

All Female Male
Number of individuals 8970 7455 1515
Unadjusted prevalence (%) 2.18 3.24 0.83
Mean age at first event (years) 42.96 42.31 46.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.96 [1.18, 3.26] 9.0e-3 181
15 years 0.01 1.68 [1.07, 2.64] 2.3e-2 94
5 years 0.00 2.60 [1.65, 4.07] 3.3e-5 44
1 year 0.00 4.52 [2.45, 8.33] 1.4e-6 15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MIGRAINE_WITH_AURA – Migraine with aura
GWS hits: 2

Survival analyses between endpoints

Plot

before Migraine with aura
after Migraine with aura

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Migraine with aura