Focal epilepsy, strict definition

FE_STRICT

partial epilepsy: A seizure caused by a localized disorder.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not GE

427728

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

FE

7083

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Remove individuals based on genotype QC

6838

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FE_STRICT

Control definitions

Control exclude G6_EPLEPSY
Control conditions not GE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 6838 3330 3508
Unadjusted prevalence (%) 1.66 1.45 1.93
Mean age at first event (years) 50.13 46.43 53.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 6.54 [4.73, 9.04] 7.4e-30 1573
15 years 0.02 2.76 [2.23, 3.43] 3.2e-20 460
5 years 0.01 6.81 [5.53, 8.40] 3.1e-72 511
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FE_STRICT – Focal epilepsy, strict definition
GWS hits:

Survival analyses between endpoints

Plot

before Focal epilepsy, strict definition
after Focal epilepsy, strict definition

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Drugs most likely to be purchased after Focal epilepsy, strict definition

Endpoint not on priority list, no data to show.