Focal epilepsy

DOID EFO MESH SNOMED Endpoint Browser PheWeb

FE

partial epilepsy: A seizure caused by a localized disorder.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G40.0, G40.1, G40.2

Hospital discharge: ICD-9 345[45]

Hospital discharge: ICD-8 3453

Cause of death: ICD-10 G40.0, G40.1, G40.2

Cause of death: ICD-9 345[45]

Cause of death: ICD-8 3453

2 out of 7 registries used, show all original rules.

7797

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Check minimum number of events None

7797

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Include endpoints None

7797

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Remove individuals based on genotype QC

7526

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FE

Control definitions

Control exclude G6_EPLEPSY

Extra metadata

First used in FinnGen datafreeze DF3

Parent code in ICD-10 G40

NAME	FE
CONTROL_EXCLUDE	G6_EPLEPSY
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G40[0-2]
HD_ICD_9	345[45]
HD_ICD_8	3453
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G40[0-2]
COD_ICD_9	345[45]
COD_ICD_8	3453
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Focal epilepsy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Focal epilepsy, strict definition

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7526	3741	3785
Unadjusted prevalence (%)	1.83	1.62	2.08
Mean age at first event (years)	48.59	44.66	52.47

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.12	6.20 [4.73, 8.13]	1.2e-39	1662
15 years	0.02	2.59 [2.04, 3.29]	5.8e-15	502
5 years	0.01	6.60 [5.51, 7.90]	1.4e-93	526
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FE – Focal epilepsy
GWS hits:

Survival analyses between endpoints

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Plot

before Focal epilepsy
after Focal epilepsy

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Table

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Drugs most likely to be purchased after Focal epilepsy

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Endpoint not on priority list, no data to show.