Specific development disorders of speech and language

DOID MESH Endpoint Browser PheWeb

F5_SPEECH

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F80

Hospital discharge: ICD-9 3153

Hospital discharge: ICD-8 3060

Cause of death: ICD-10 F80

Cause of death: ICD-9 3153

Cause of death: ICD-8 3060

2 out of 7 registries used, show all original rules.

1961

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Check minimum number of events None

1961

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Include endpoints

F5_SPECIFIC_SPEECH

1961

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Remove individuals based on genotype QC

1826

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F5_SPEECH

Control definitions

Control exclude F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF9

Parent code in ICD-10 F80-F89

Name in latin Perturbationes specificae progressus dictionis et linguae

NAME	F5_SPEECH
CONTROL_EXCLUDE	F5_PSYCHDEV
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	F5_SPECIFIC_SPEECH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F80
HD_ICD_9	3153
HD_ICD_8	3060
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F80
COD_ICD_9	3153
COD_ICD_8	3060
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Specific development disorders of speech and language based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Disorders of speech understanding and production

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1826	843	983
Unadjusted prevalence (%)	0.44	0.37	0.54
Mean age at first event (years)	22.91	26.93	19.47

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.31	18.76 [11.95, 29.45]	3.8e-37	97
15 years	0.02	3.18 [1.83, 5.51]	4.0e-5	15
5 years	0.01	8.07 [4.37, 14.88]	2.3e-11	28
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_SPEECH – Specific development disorders of speech and language
GWS hits: 1

Survival analyses between endpoints

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Plot

before Specific development disorders of speech and language
after Specific development disorders of speech and language

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Table

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Drugs most likely to be purchased after Specific development disorders of speech and language

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Endpoint not on priority list, no data to show.