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Post-traumatic stress disorder

DOID EFO MESH SNOMED Endpoint Browser PheWeb

F5_PTSD

post-traumatic stress disorder: An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F43.1
Hospital discharge: ICD-9 3098X
Cause of death: ICD-10 F43.1
Cause of death: ICD-9 3098X

2 out of 7 registries used, show all original rules.

2839

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Check minimum number of events None

2839

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Include endpoints None

2839

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Remove individuals based on genotype QC

2615

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F5_PTSD

Control definitions

Control exclude F5_NEUROTIC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F43
Name in latin Perturbatio stressualis posttraumatica

Summary Statistics

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Key figures

All Female Male
Number of individuals 2615 2152 463
Unadjusted prevalence (%) 0.63 0.93 0.25
Mean age at first event (years) 35.73 34.82 39.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.60 [1.28, 5.27] 8.0e-3 70
15 years 0.02 2.25 [1.21, 4.17] 1.0e-2 36
5 years 0.01 4.38 [2.25, 8.50] 1.3e-5 18
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_PTSD – Post-traumatic stress disorder
GWS hits:

Survival analyses between endpoints

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Plot

before Post-traumatic stress disorder
after Post-traumatic stress disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Post-traumatic stress disorder

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Endpoint not on priority list, no data to show.