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Psychotic depression

Endpoint Browser PheWeb

F5_DEPRESSION_PSYCHOTIC

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not (F5_SCHIZO
or F5_SCHIZOAFF
or F5_BIPO

409530

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Check pre-conditions, main-only, mode, registry filters

Primary healthcare outpatient: ICD-10: F32.3, F33.3
Hospital Discharge: ICD-10 F32.3, F33.3
Hospital discharge: ICD-9 2961E
Cause of death: ICD-10 F32.3, F33.3
Cause of death: ICD-9 2961E

3 out of 7 registries used, show all original rules.

2248

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Check minimum number of events None

2248

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Include endpoints None

2248

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Remove individuals based on genotype QC

2149

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F5_DEPRESSION_PSYCHOTIC

Control definitions

Control exclude F5_PSYCH, ANTIDEPRESSANTS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF9

Summary Statistics

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Key figures

All Female Male
Number of individuals 2149 1349 800
Unadjusted prevalence (%) 0.52 0.59 0.44
Mean age at first event (years) 46.48 43.92 50.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.21 [1.13, 4.30] 2.0e-2 237
15 years 0.01 1.69 [1.08, 2.65] 2.1e-2 111
5 years 0.00 2.77 [1.90, 4.03] 1.1e-7 61
1 year 0.00 7.31 [4.66, 11.47] 4.7e-18 31

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_DEPRESSION_PSYCHOTIC – Psychotic depression
GWS hits:

Survival analyses between endpoints

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Plot

before Psychotic depression
after Psychotic depression

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psychotic depression

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Endpoint not on priority list, no data to show.