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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Thyrotoxicosis, other and/or unspecified


Thyrotoxicosis: A hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. Signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. Causes include Graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E05[4-9]
Hospital discharge: ICD-9 2423
Hospital discharge: ICD-8 2422
Cause of death: ICD-10 E05[4-9]
Cause of death: ICD-9 2423
Cause of death: ICD-8 2422
Medicine purchases: ATC H03B

3 out of 7 registries used, show all original rules.


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Check minimum number of events

Min. number of events 3


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6967 5450 1517
Unadjusted prevalence (%) 1.69 2.37 0.83
Mean age at first event (years) 52.47 50.93 58.01


Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.


Index endpoint: E4_THYTOXNAS – Thyrotoxicosis, other and/or unspecified
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Thyrotoxicosis, other and/or unspecified

Endpoint not on priority list, no data to show.