Graves ophthalmopathy, strict

E4_GRAVES_OPHT_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H06.2*E05.9
Cause of death: ICD-10 H06.2*E05.9

2 out of 7 registries used, show all original rules.

622

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Check minimum number of events None

622

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Include endpoints None

622

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Remove individuals based on genotype QC

598

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E4_GRAVES_OPHT_STRICT

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 598 484 114
Unadjusted prevalence (%) 0.15 0.21 0.06
Mean age at first event (years) 52.15 51.56 54.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.59 [0.21, 1.64] 3.1e-1 25
15 years 0.00 0.50 [0.20, 1.27] 1.5e-1 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_GRAVES_OPHT_STRICT – Graves ophthalmopathy, strict
GWS hits:

Survival analyses between endpoints

Plot

before Graves ophthalmopathy, strict
after Graves ophthalmopathy, strict

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Graves ophthalmopathy, strict

Endpoint not on priority list, no data to show.