Testicular hypofunction

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only males

189303

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Check conditions None

189303

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E29.1#
Hospital discharge: ICD-9 257[1-2]
Hospital discharge: ICD-8 2571
Cause of death: ICD-10 E29.1#
Cause of death: ICD-9 257[1-2]
Cause of death: ICD-8 2571
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E29.1#

3 out of 7 registries used, show all original rules.

810

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Check minimum number of events None

810

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Include endpoints None

810

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Remove individuals based on genotype QC

782

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E4_TESTICHYPO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E29
Name in latin Hypofunctio testium

Summary Statistics

Key figures

All Female Male
Number of individuals 782 - 782
Unadjusted prevalence (%) 0.19 - 0.43
Mean age at first event (years) 50.57 - 50.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 4.91 [2.24, 10.79] 7.3e-5 35
15 years 0.03 3.19 [1.50, 6.78] 2.6e-3 19
5 years 0.01 4.59 [2.03, 10.40] 2.6e-4 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_TESTICHYPO – Testicular hypofunction
GWS hits:

Survival analyses between endpoints

Plot

before Testicular hypofunction
after Testicular hypofunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Testicular hypofunction

Endpoint not on priority list, no data to show.