≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Testicular hypofunction

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only males

189303

diagram downward connector

Check conditions None

189303

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E29.1#
Hospital discharge: ICD-9 257[1-2]
Hospital discharge: ICD-8 2571
Cause of death: ICD-10 E29.1#
Cause of death: ICD-9 257[1-2]
Cause of death: ICD-8 2571
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E29.1#

3 out of 7 registries used, show all original rules.

810

diagram downward connector

Check minimum number of events None

810

diagram downward connector

Include endpoints None

810

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

782

diagram downward connector
E4_TESTICHYPO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E29
Name in latin Hypofunctio testium

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 782 - 782
Unadjusted prevalence (%) 0.19 - 0.43
Mean age at first event (years) 50.57 - 50.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 4.91 [2.24, 10.79] 7.3e-5 35
15 years 0.03 3.19 [1.50, 6.78] 2.6e-3 19
5 years 0.01 4.59 [2.03, 10.40] 2.6e-4 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_TESTICHYPO – Testicular hypofunction
GWS hits:

Survival analyses between endpoints

↥

Plot

before Testicular hypofunction
after Testicular hypofunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Testicular hypofunction

↥

Endpoint not on priority list, no data to show.