This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Lactose intolerance
DOID EFO MESH SNOMED Endpoint Browser
E4_LACTOSEINT
lactose intolerance: Inability to fully digest and absorb lactose due to limited or no lactase activity in the small intestine. Congenital intolerance is inherited following an autosomal recessive pattern but is rare. It is more often due to a gradual decline of lactase production in adulthood following the ingestion of fewer lactose-containing foods or secondary to an intestinal mucosal brush-border injury. Prevalence is highest among Asians, Native Americans and Africans. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following the dietary intake of lactose.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions None
429209
Check pre-conditions, main-only, mode, registry filters
2 out of 7 registries used, show all original rules.
710
Check minimum number of events None
710
Remove individuals based on genotype QC
905
E4_LACTOSEINT
Control definitions
Control exclude
E4_METABOLIA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E70-E90
Name in latin
Intolerantia lactosi
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Lactose intolerance
based on the number of shared cases.
Broader endpoints:
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 905 | 615 | 290 |
| Unadjusted prevalence (%) | 0.22 | 0.27 | 0.16 |
| Mean age at first event (years) | 39.50 | 38.86 | 40.87 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: E4_LACTOSEINT – Lactose intolerance
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Lactose intolerance
↥Endpoint not on priority list, no data to show.