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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Lactose intolerance

E4_LACTOSEINT

lactose intolerance: Inability to fully digest and absorb lactose due to limited or no lactase activity in the small intestine. Congenital intolerance is inherited following an autosomal recessive pattern but is rare. It is more often due to a gradual decline of lactase production in adulthood following the ingestion of fewer lactose-containing foods or secondary to an intestinal mucosal brush-border injury. Prevalence is highest among Asians, Native Americans and Africans. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following the dietary intake of lactose.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E73
Cause of death: ICD-10 E73

2 out of 7 registries used, show all original rules.

710

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Check minimum number of events None

710

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Include endpoints

960

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Remove individuals based on genotype QC

905

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E4_LACTOSEINT

Control definitions

Control exclude E4_METABOLIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E70-E90
Name in latin Intolerantia lactosi

Summary Statistics

Key figures

All Female Male
Number of individuals 905 615 290
Unadjusted prevalence (%) 0.22 0.27 0.16
Mean age at first event (years) 39.50 38.86 40.87

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: E4_LACTOSEINT – Lactose intolerance
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Lactose intolerance

Endpoint not on priority list, no data to show.