Hypothalamic dysfunction, including iatrogenic, not elsewhere classified

DOID MESH Endpoint Browser PheWeb

E4_HYPOTHALDYSF

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E23.1#, E23.3

Hospital discharge: ICD-9 2537

Cause of death: ICD-10 E23.1#, E23.3

Cause of death: ICD-9 2537

2 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints None

Remove individuals based on genotype QC

E4_HYPOTHALDYSF

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

NAME	E4_HYPOTHALDYSF
CONTROL_EXCLUDE	E4_ENDOGLAND
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E231\|E233
HD_ICD_9	2537
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E231\|E233
COD_ICD_9	2537
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Hypothalamic dysfunction, including iatrogenic, not elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Drug-induced hypopituitarism

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	58	35	23
Unadjusted prevalence (%)	0.01	0.02	0.01
Mean age at first event (years)	37.57	37.73	37.32

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPOTHALDYSF – Hypothalamic dysfunction, including iatrogenic, not elsewhere classified
GWS hits:

Survival analyses between endpoints

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Plot

before Hypothalamic dysfunction, including iatrogenic, not elsewhere classified
after Hypothalamic dysfunction, including iatrogenic, not elsewhere classified

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Table

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Drugs most likely to be purchased after Hypothalamic dysfunction, including iatrogenic, not elsewhere classified

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Endpoint not on priority list, no data to show.

≡ Risteys

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