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Other endocrine disorders

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_ENDODIS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E34, E35
Cause of death: ICD-10 E34, E35

2 out of 7 registries used, show all original rules.

1692

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Check minimum number of events None

1692

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Include endpoints

1792

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Remove individuals based on genotype QC

1701

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E4_ENDODIS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1701 1016 685
Unadjusted prevalence (%) 0.41 0.44 0.38
Mean age at first event (years) 29.51 28.43 31.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.33 [2.51, 7.49] 1.5e-7 121
15 years 0.02 2.48 [1.44, 4.27] 1.1e-3 56
5 years 0.01 5.03 [3.05, 8.27] 2.2e-10 34
1 year 0.00 9.88 [5.24, 18.65] 1.5e-12 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDODIS – Other endocrine disorders
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other endocrine disorders
after Other endocrine disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other endocrine disorders

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Endpoint not on priority list, no data to show.