Other disorders of amino-acid metabolism

DOID MESH Endpoint Browser PheWeb

E4_AMINO

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E72

Cause of death: ICD-10 E72

2 out of 7 registries used, show all original rules.

127

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Check minimum number of events None

127

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Include endpoints

E4_AMINOTRANSPORT

E4_GLYCINE

E4_AMINONAS

145

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Remove individuals based on genotype QC

141

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E4_AMINO

Control definitions

Control exclude E4_METABOLIA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E70-E90

Name in latin Aliae perturbationes metabolismi acidorum aminoicorum

NAME	E4_AMINO
CONTROL_EXCLUDE	E4_METABOLIA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	E4_AMINOTRANSPORT\|E4_SULFURMET\|E4_UREACYCLE\|E4_LYSINEHYDRO\|E4_ORNITHINE\|E4_GLYCINE\|E4_AMINONAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E72
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E72
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other disorders of amino-acid metabolism based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	141	74	67
Unadjusted prevalence (%)	0.03	0.03	0.04
Mean age at first event (years)	46.73	43.22	50.60

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_AMINO – Other disorders of amino-acid metabolism
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other disorders of amino-acid metabolism
after Other disorders of amino-acid metabolism

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Table

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Drugs most likely to be purchased after Other disorders of amino-acid metabolism

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Endpoint not on priority list, no data to show.