Other adrenocortical overactivity

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_ADREACT

adrenal gland disease: A disease involving the adrenal gland.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E27.0

Hospital discharge: ICD-9 2553A

Hospital discharge: ICD-8 25508

Cause of death: ICD-10 E27.0

Cause of death: ICD-9 2553A

Cause of death: ICD-8 25508

2 out of 7 registries used, show all original rules.

173

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Check minimum number of events None

173

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Include endpoints None

173

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Remove individuals based on genotype QC

165

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E4_ADREACT

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E27

Name in latin Alia hyperfunctio adrenocorticalis

NAME	E4_ADREACT
CONTROL_EXCLUDE	E4_ENDOGLAND
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E270
HD_ICD_9	2553A
HD_ICD_8	25508
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E270
COD_ICD_9	2553A
COD_ICD_8	25508
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other adrenocortical overactivity based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	165	134	31
Unadjusted prevalence (%)	0.04	0.06	0.02
Mean age at first event (years)	23.76	19.51	42.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ADREACT – Other adrenocortical overactivity
GWS hits:

Survival analyses between endpoints

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Plot

before Other adrenocortical overactivity
after Other adrenocortical overactivity

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Table

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Drugs most likely to be purchased after Other adrenocortical overactivity

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Endpoint not on priority list, no data to show.