Diabetic nephropathy (more control exclusions)

Endpoint Browser PheWeb

DM_NEPHROPATHY_EXMORE

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

Apply sex-specific rule None

Check conditions None

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N08.3*

Cause of death: ICD-10 N08.3*

2 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints

DM_KIDNEYFAIL

DM_DIALYSIS

DM_KIDNEYTRANSPLANT

Remove individuals based on genotype QC

4433

DM_NEPHROPATHY_EXMORE

Control definitions

Control exclude DIABETES_FG

Extra metadata

First used in FinnGen datafreeze DF2

NAME	DM_NEPHROPATHY_EXMORE
CONTROL_EXCLUDE	DIABETES_FG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	DM_KIDNEYFAIL\|DM_DIALYSIS\|DM_KIDNEYTRANSPLANT
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N083
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N083
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

No upset plot: script not run.

No upset table: script not run.

Similar endpoints

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List of similar endpoints to Diabetic nephropathy (more control exclusions) based on the number of shared cases.

Broader endpoints:

Any event in hilmo or specialist outpatient

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4433	1545	2888
Unadjusted prevalence (%)	1.08	0.67	1.59
Mean age at first event (years)	55.77	50.04	58.84

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.18	9.89 [7.10, 13.78]	9.7e-42	1456
15 years	0.03	4.25 [3.21, 5.63]	7.3e-24	498
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_NEPHROPATHY_EXMORE – Diabetic nephropathy (more control exclusions)
GWS hits: 6

Survival analyses between endpoints

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Plot

before Diabetic nephropathy (more control exclusions)
after Diabetic nephropathy (more control exclusions)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Diabetic nephropathy (more control exclusions)

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Endpoint not on priority list, no data to show.

≡ Risteys

R10

R9

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R7

R6

R5

R4

R3