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Other diseases of blood and blood-forming organs

DOID EFO MESH SNOMED Endpoint Browser PheWeb

D3_OTHERBLOOD

hematologic disease: A disease involving the hematopoietic system.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D75
Cause of death: ICD-10 D75

2 out of 7 registries used, show all original rules.

1993

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Check minimum number of events None

1993

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Include endpoints

2113

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Remove individuals based on genotype QC

2059

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D3_OTHERBLOOD

Control definitions

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D70-D77
Name in latin Alii morbi sanguinis et organorum haematopoeticorum

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 2059 1001 1058
Unadjusted prevalence (%) 0.50 0.43 0.58
Mean age at first event (years) 57.18 56.18 58.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 3.84 [2.76, 5.34] 1.4e-15 343
15 years 0.02 2.30 [1.69, 3.14] 1.4e-7 165
5 years 0.00 3.27 [2.50, 4.29] 6.6e-18 98
1 year 0.00 9.02 [6.48, 12.55] 7.6e-39 53

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_OTHERBLOOD – Other diseases of blood and blood-forming organs
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other diseases of blood and blood-forming organs
after Other diseases of blood and blood-forming organs

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Drugs most likely to be purchased after Other diseases of blood and blood-forming organs

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Endpoint not on priority list, no data to show.