Other and unspecified diseases of blood and blood-forming organs

D3_BLOODNAS

hematologic disease: A disease involving the hematopoietic system.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D75.8, D75.9
Hospital discharge: ICD-9 289[8-9]
Hospital discharge: ICD-8 2899
Hospital discharge: excluded ICD-8 2899[0-1]
Cause of death: ICD-10 D75.8, D75.9
Cause of death: ICD-9 289[8-9]
Cause of death: ICD-8 2899
Cause of death: excluded ICD-8 2899[0-1]

2 out of 7 registries used, show all original rules.

726

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Check minimum number of events None

726

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Include endpoints None

726

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Remove individuals based on genotype QC

705

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D3_BLOODNAS

Control definitions

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 705 367 338
Unadjusted prevalence (%) 0.17 0.16 0.19
Mean age at first event (years) 55.83 54.35 57.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.56 [2.34, 8.87] 8.1e-6 125
15 years 0.02 2.34 [1.34, 4.08] 2.8e-3 49
5 years 0.01 3.86 [2.02, 7.37] 4.5e-5 37
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_BLOODNAS – Other and unspecified diseases of blood and blood-forming organs
GWS hits: 1

Survival analyses between endpoints

Plot

before Other and unspecified diseases of blood and blood-forming organs
after Other and unspecified diseases of blood and blood-forming organs

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Drugs most likely to be purchased after Other and unspecified diseases of blood and blood-forming organs

Endpoint not on priority list, no data to show.