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Other coagulation defects

DOID EFO MESH SNOMED Endpoint Browser PheWeb

D3_COAGOTHER

thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D68
Cause of death: ICD-10 D68

2 out of 7 registries used, show all original rules.

2191

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Check minimum number of events None

2191

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Include endpoints

2233

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Remove individuals based on genotype QC

2154

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D3_COAGOTHER

Control definitions

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D65-D69
Name in latin Aliae defectus coagulationis

Similar endpoints

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List of similar endpoints to Other coagulation defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2154 1449 705
Unadjusted prevalence (%) 0.52 0.63 0.39
Mean age at first event (years) 48.86 44.26 58.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.79 [1.06, 7.34] 3.7e-2 326
15 years 0.00 0.55 [0.20, 1.54] 2.6e-1 55
5 years 0.00 1.60 [0.69, 3.70] 2.7e-1 44
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGOTHER – Other coagulation defects
GWS hits: 33

Survival analyses between endpoints

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Plot

before Other coagulation defects
after Other coagulation defects

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Drugs most likely to be purchased after Other coagulation defects

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Endpoint not on priority list, no data to show.