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Other and unspecified coagulation defects

DOID EFO MESH SNOMED Endpoint Browser PheWeb

D3_COAGDEFNAS

blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D68.8, D68.9
Hospital discharge: ICD-9 2869
Hospital discharge: ICD-8 2869
Cause of death: ICD-10 D68.8, D68.9
Cause of death: ICD-9 2869
Cause of death: ICD-8 2869

2 out of 7 registries used, show all original rules.

1422

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Check minimum number of events None

1422

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Include endpoints None

1422

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Remove individuals based on genotype QC

1375

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D3_COAGDEFNAS

Control definitions

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1375 975 400
Unadjusted prevalence (%) 0.33 0.42 0.22
Mean age at first event (years) 46.71 43.96 53.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 5.13 [3.01, 8.72] 1.6e-9 100
15 years 0.02 2.66 [1.63, 4.34] 8.4e-5 38
5 years 0.01 4.69 [2.65, 8.31] 1.1e-7 28
1 year 0.00 18.26 [9.86, 33.82] 2.6e-20 24

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGDEFNAS – Other and unspecified coagulation defects
GWS hits: 28

Survival analyses between endpoints

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Plot

before Other and unspecified coagulation defects
after Other and unspecified coagulation defects

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified coagulation defects

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Endpoint not on priority list, no data to show.