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Agranulocytosis

DOID MESH Endpoint Browser PheWeb

D3_AGRANULOCYTOSIS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D70
Hospital discharge: ICD-9 2880
Hospital discharge: ICD-8 2889
Cause of death: ICD-10 D70
Cause of death: ICD-9 2880
Cause of death: ICD-8 2889

2 out of 7 registries used, show all original rules.

3584

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Check minimum number of events None

3584

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Include endpoints None

3584

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Remove individuals based on genotype QC

3462

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D3_AGRANULOCYTOSIS

Control definitions

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D70-D77
Name in latin Agranulocytosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 3462 2194 1268
Unadjusted prevalence (%) 0.84 0.95 0.70
Mean age at first event (years) 56.67 54.74 59.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.33 19.84 [12.44, 31.65] 4.3e-36 798
15 years 0.02 3.47 [2.32, 5.20] 1.4e-9 108
5 years 0.03 19.64 [14.41, 26.77] 2.7e-79 288
1 year 0.02 107.36 [84.81, 135.90] <1e-100 389

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_AGRANULOCYTOSIS – Agranulocytosis
GWS hits:

Survival analyses between endpoints

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Plot

before Agranulocytosis
after Agranulocytosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Agranulocytosis

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Endpoint not on priority list, no data to show.