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Crohn's disease of large intestine

DOID EFO MESH Endpoint Browser PheWeb

CHRONLARGE

Crohn's colitis: Crohn's disease affecting the colon.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K50.1
Cause of death: ICD-10 K50.1

2 out of 7 registries used, show all original rules.

1789

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Check minimum number of events None

1789

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Include endpoints None

1789

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Remove individuals based on genotype QC

1731

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CHRONLARGE

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Colitis regionalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 1731 975 756
Unadjusted prevalence (%) 0.42 0.42 0.42
Mean age at first event (years) 42.91 41.66 44.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.45 [0.43, 4.92] 5.5e-1 91
15 years 0.01 1.35 [0.57, 3.21] 5.0e-1 46
5 years 0.00 1.92 [0.94, 3.92] 7.5e-2 20
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHRONLARGE – Crohn's disease of large intestine
GWS hits: 7

Survival analyses between endpoints

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Plot

before Crohn's disease of large intestine
after Crohn's disease of large intestine

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Crohn's disease of large intestine

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Endpoint not on priority list, no data to show.