Non-small cell lung cancer, squamous (controls excluding all cancers)

C3_NSCLC_SQUAM_EXALLC

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions

HLP_C3_NSCLC_SQUAM

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C34
Cause of death: ICD-9 162
Cause of death: ICD-8 162
Cancer registry: Topography ICD-O-3 C34
Cancer registry: Morphology ICD-O-3 8070
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

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Remove individuals based on genotype QC

1510

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C3_NSCLC_SQUAM_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE
Control conditions not HLP_C3_NSCLC_SQUAM

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 1510 175 1335
Unadjusted prevalence (%) 0.37 0.08 0.73
Mean age at first event (years) 71.29 68.60 71.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.28 15.08 [9.38, 24.22] 3.5e-29 1047
15 years 0.01 1.63 [1.06, 2.49] 2.5e-2 97
5 years 0.02 12.34 [10.01, 15.22] <1e-100 378
1 year 0.01 51.38 [44.33, 59.54] <1e-100 562

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_NSCLC_SQUAM_EXALLC – Non-small cell lung cancer, squamous (controls excluding all cancers)
GWS hits: 2

Survival analyses between endpoints

Plot

before Non-small cell lung cancer, squamous (controls excluding all cancers)
after Non-small cell lung cancer, squamous (controls excluding all cancers)

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Drugs most likely to be purchased after Non-small cell lung cancer, squamous (controls excluding all cancers)

Endpoint not on priority list, no data to show.