Non-small cell lung cancer (controls excluding all cancers)

C3_LUNG_NONSMALL_EXALLC

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C34.[123457]
Cause of death: ICD-10 C34.[123457]
Cancer registry: Topography ICD-O-3 C34
Cancer registry: Morphology ICD-O-3 8046|8070|8140
Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

5315

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C3_LUNG_NONSMALL_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF9

Similar endpoints

List of similar endpoints to Non-small cell lung cancer (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 5315 1465 3850
Unadjusted prevalence (%) 1.29 0.64 2.12
Mean age at first event (years) 70.30 67.37 71.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.29 15.42 [7.68, 30.95] 1.4e-14 3007
15 years 0.01 1.84 [1.21, 2.80] 4.6e-3 217
5 years 0.02 14.84 [12.12, 18.17] <1e-100 952
1 year 0.02 70.09 [61.86, 79.40] <1e-100 1813

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_LUNG_NONSMALL_EXALLC – Non-small cell lung cancer (controls excluding all cancers)
GWS hits: 5

Survival analyses between endpoints

Plot

before Non-small cell lung cancer (controls excluding all cancers)
after Non-small cell lung cancer (controls excluding all cancers)

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Drugs most likely to be purchased after Non-small cell lung cancer (controls excluding all cancers)

Endpoint not on priority list, no data to show.