Autoimmune diseases excluding thyroid diseases, strict definition

AUTOIMMUNE_NONTHYROID_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not (HYPOTHY_LEVOTHY
or GRAVES_COND
or E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM

372379

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

58619

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Remove individuals based on genotype QC

56628

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AUTOIMMUNE_NONTHYROID_STRICT

Control definitions

Control conditions not (HYPOTHY_LEVOTHY
or GRAVES_COND
or E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 56628 29869 26759
Unadjusted prevalence (%) 13.75 12.97 14.72
Mean age at first event (years) 45.60 43.57 47.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.35 [2.11, 2.62] 1.4e-53 7362
15 years 0.01 1.60 [1.46, 1.75] 3.2e-24 3148
5 years 0.00 2.74 [2.52, 2.98] <1e-100 1757
1 year 0.00 5.77 [5.15, 6.45] <1e-100 731

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AUTOIMMUNE_NONTHYROID_STRICT – Autoimmune diseases excluding thyroid diseases, strict definition
GWS hits: 57

Survival analyses between endpoints

Plot

before Autoimmune diseases excluding thyroid diseases, strict definition
after Autoimmune diseases excluding thyroid diseases, strict definition

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Drugs most likely to be purchased after Autoimmune diseases excluding thyroid diseases, strict definition

Endpoint not on priority list, no data to show.