Autoimmune diseases excluding thyroid diseases

AUTOIMMUNE_NONTHYROID

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not (E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM
or E4_GRAVES_STRICT

379002

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

60184

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Remove individuals based on genotype QC

58156

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AUTOIMMUNE_NONTHYROID

Control definitions

Control conditions not (E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM
or E4_GRAVES_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 58156 31048 27108
Unadjusted prevalence (%) 14.12 13.49 14.92
Mean age at first event (years) 45.65 43.71 47.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.31 [2.06, 2.60] 9.8e-45 7500
15 years 0.01 1.62 [1.47, 1.78] 5.0e-23 3201
5 years 0.00 2.78 [2.56, 3.03] <1e-100 1775
1 year 0.00 5.82 [5.20, 6.52] <1e-100 740

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AUTOIMMUNE_NONTHYROID – Autoimmune diseases excluding thyroid diseases
GWS hits: 62

Survival analyses between endpoints

Plot

before Autoimmune diseases excluding thyroid diseases
after Autoimmune diseases excluding thyroid diseases

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Drugs most likely to be purchased after Autoimmune diseases excluding thyroid diseases

Endpoint not on priority list, no data to show.