Asthma-related acute respiratory infections

ASTHMA_ACUTE_RESPIRATORY_INFECTIONS

bronchitis: An acute or chronic inflammatory process affecting the bronchi. [database_cross_reference: NCIT:C2911]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

J10_ASTHMA

48366

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

17809

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ASTHMA_ACUTE_RESPIRATORY_INFECTIONS

Control definitions

Control exclude ASTHMA_INFECTIONS
Control conditions not J10_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 17809 10589 7220
Unadjusted prevalence (%) 4.32 4.60 3.97
Mean age at first event (years) 39.94 40.80 38.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.44 [2.89, 4.09] 2.6e-44 2123
15 years 0.01 1.79 [1.53, 2.11] 1.3e-12 827
5 years 0.00 3.56 [3.09, 4.10] 2.5e-69 627
1 year 0.00 8.67 [7.35, 10.22] <1e-100 303

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ASTHMA_ACUTE_RESPIRATORY_INFECTIONS – Asthma-related acute respiratory infections
GWS hits: 17

Survival analyses between endpoints

Plot

before Asthma-related acute respiratory infections
after Asthma-related acute respiratory infections

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Asthma-related acute respiratory infections

Endpoint not on priority list, no data to show.